![]() Sleep also plays an important role in energy conservation and the regulation of hormones and our metabolism. It’s necessary for the memory and cognitive functions of the brain to operate normally. Eventually, sleep becomes impossible.Īs you know, sufficient sleep is vital for the health of your brain and the rest of your body. You may twitch or kick involuntarily while you sleep. You may have increasing difficulty falling or staying asleep. These conditions damage the thalamus to the point at which the brain remains in a state of wakefulness. This is the part of the brain that helps control your sleep/wake cycles. Unlike other prion diseases that can affect various regions of the brain, fatal familial insomnia and sporadic fatal insomnia primarily affect one part of the brain-the thalamus. Fatal Familial Insomnia: Symptoms and Diagnosis With sporadic fatal insomnia, the prion proteins spontaneously change into the unhealthy versions. In the case of fatal familial insomnia, the gene is passed from one or more parents to their child. This mutation leads to the formation of abnormal prion proteins, which clump together in the brain and damage healthy neurons. People with the disease have a mutation in the gene responsible for manufacturing prion proteins. This is because they are diseases that affect prion proteins, which are found throughout the brain. What Causes Fatal Familial Insomnia?īoth fatal familial insomnia and sporadic fatal insomnia are among a group of conditions known as prion diseases. ![]() Fewer than 100 people worldwide are known to have the disease. Fatal familial insomnia is an inherited condition, while a related disease called sporadic fatal insomnia has no genetic component. And because there is no cure, the disease eventually takes their life. And for many people, advancing age, an underlying medical condition like Parkinson’s disease, or just poor sleep habits are to blame.īut in extremely rare cases, a brain condition known as fatal familial insomnia (FFI) robs people of their sleep. For others, the problem is prescription medication or too much caffeine. ![]() For some people, stress or depression keeps them from getting a good night’s sleep. Insomnia takes on many forms and has many causes. ![]()
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